How do i set the bits for highest signal to noise ratio at 10kHz correctly?

Hello Labjack-Forum,

my circuit looks like this from another Forum post of mine. https://labjack.com/sites/default/files/forums/Idea_1.png , https://labjack.com/forums/u3/difference-between-my-circuit-and-picture-using-ground-input

1.) I want to sample data with a frequency of 10kHz and i use 2 Analog Inputs ( single-ended, MAX samples/sec = 20000 ).

Im rather confused about my PChannels and NChannels parameters since i use the dedicated AIN0 / AIN1 and GND on my LJ U3

Can you confirm my streamConfig-Parameters and( Python ):

d= u3.U3()

# To learn the if the U3 is an HV
d.configU3()

# For applying the proper calibration to readings.
d.getCalibrationData()

# Set the FIO0 and FIO1 to Analog (d3 = b00000011)
#d.configIO(FIOAnalog=3)

No configIO needed for using the dedicated AIN0 and AIN1 right ?

d.streamConfig(NumChannels=2, PChannels=[31 31], NChannels=[31, 31], Resolution=2, ScanFrequency=10000)

2.) I have also heard from other Posts on this forum, that someone got problems with noise and he got suggested to change some Code on the streamTest.py to the following:

d.streamPacketOffset = 0

for r in d.streamData(convert=False):

and then converting it later, instead of

for r in d.streamData():

Are there any other Parameters that i can adjust for best measuring that i should be aware of ? 

Thanking you in Advance,

Benjamin